2009 H1N1 Influenza
As of October 2, 2009:
–World Health Organization (WHO) regions have reported over 343,298 laboratory-confirmed cases
–At least 4,108 deaths
–The laboratory-confirmed cases represent a substantial underestimation of total cases
• Oseltamivir (Tamiflu) and Zanamivir (Relenza)
• Randomized clinical trials (RCT): Reduced duration of influenza by 1-1.5 days when administered in 48 hours
• Pooled RCT analysis: Reduced lower respiratory tract complications, pneumonia, and hospitalization
• Observational studies*: Oseltamivir reduced mortality among hospitalized adults with lab-confirmed seasonal influenza A virus infections