The Multi-State Information Sharing and Analysis Center (MS-ISAC) assesses with high confidence that cyber threat actors routinely target universities, for the purposes of financial gain, notoriety, or entertainment, and often to gain access to personally identifiable information (PII) and/or sensitive research. MS-ISAC believes universities are inherently more vulnerable to cyber targeting than other state, local, tribal, and territorial (SLTT) government entities, due to the non-restrictive research environment with less compartmentalization and less access restriction, which results in more opportunity for infection, and when infection occurs, easier transmission through a network.