Topic: Drugs/Opiates/Fentanyl

    (U//FOUO) Michigan High Intensity Drug Trafficking Area Threat Assessment 2023

    The threat from the production, use, and trafficking of illegal drugs throughout the State of Michigan continues to be of great concern. In 2022, the demand and availability of some commonly used drugs increased while others slightly decreased compared to 2021. Also, several drugs showed an increase in use, while others showed a slight decrease throughout the state during the 2022 reporting period. According to drug teams’ survey responses on the most significant threat in their area of responsibility (AOR), as well as contributing factors such as availability and seizures, the drug threat ranking has remained the same from the previous reporting period.

    (U//LES) DEA Bulletin: Expanding Fentanyl Threat in the United States

    Fentanyl is a Schedule II synthetic opioid originally developed to serve as both an analgesic (painkiller) and an anesthetic; however, its strong opioid properties have made it an attractive drug of abuse in the United States. Fentanyl, in its licit form, is diverted from the market on a small scale for personal use or sale. Illicitly manufactured and trafficked fentanyl is responsible for the current domestic crisis. Fentanyl, fentanyl-related compounds, and the precursor chemicals needed to produce these substances originate in China and transit Mexico or Canada enroute to U.S. markets. It is believed that illicit fentanyl manufacturing is occurring in Mexico. Moreover, small-scale production facilities have been discovered in the United States and Canada.

    InterAgency Board Recommendations on Personal Protective Equipment and Decontamination Products for Fentanyl Exposure

    Increased illicit use of opioids, including synthetic opioids such as fentanyl and its analogue carfentanil, is a source of increased risk to responders. Most routine encounters between patients or detainees and EMS or law enforcement do not present a significant threat of toxic exposure. While there are anecdotal reports of public safety personnel being exposed to opioids during operations, they are largely unconfirmed. To proactively address the potential risks, this document establishes guidance for personal protective equipment selection and use, decontamination, detection, and medical countermeasures for first responders who may be exposed to opioids in the course of their occupational activities. Throughout the remainder of this document, the term synthetic opioids will be used to include fentanyl, fentanyl analogues, morphine analogues, the U-series opioids, and others.

    Customs and Border Protection Alert: Fentanyl Analogues Not Resistant to Narcan (Naloxone)

    Contrary to recent news reporting, there are no fentanyl analogues resistant to Naloxone. News reports indicated a “new” fentanyl analogue, acrylfentanyl, was “extremely powerful” and implied it resisted Naloxone’s effects. However, acrylfentanyl binds to the same receptors within the human body as fentanyl, meaning correctly administered Naloxone is effective against it.

    DEA Analysis of Overdose Deaths in Pennsylvania 2016

    The analysis of drug-related overdose death data plays a pivotal role in law enforcement’s efforts to identify and combat drug suppliers, and ultimately drug abuse and related overdoses. At the most basic level, the drugs that contribute to death are an indicator of drug availability in the user market. Analysis of this data also highlights geographic patterns of abuse and identifies at-risk populations, and when coupled with drug treatment statistics, law enforcement drug seizure data, and public health indicators, allows for multi-disciplinary data-driven decisions regarding resource placement and strategic initiatives.

    (U//LES) DEA Fentanyl Briefing Guide for First Responders

    In the last several years, U.S. Law Enforcement has seen a dramatic increase in the availability of dangerous synthetic opioids. A large majority of these synthetic opioids are structural derivatives of the synthetic drug “fentanyl.” Fentanyl is a synthetic opioid currently listed as a Schedule II prescription drug that mimics the effects of morphine in the human body, but has potency 50–100 times that of morphine. Due to the high potency and availability of fentanyl, both transnational and domestic criminal organizations are increasingly utilizing these dangerous synthetic opioids as an adulterant in heroin and other controlled substances. The presence of these synthetic opioids in the illicit U.S. drug market is extremely concerning as the potency of these drugs has led to a significant increase in overdose incidents and overdose-related deaths throughout the nation.